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Year : 2014  |  Volume : 4  |  Issue : 6  |  Page : 193-198

Estimation of salivary β-glucuronidase activity as a marker of periodontal disease: A case control study

1 Department of Periodontology, Best Dental Science College, Madurai, India
2 Department of Oral and Maxillofacial Surgery, CSI College of Dental Sciences and Research, Madurai, India
3 Department of Conservative Dentistry and Endodontics, CSI College of Dental Sciences and Research, Madurai, India
4 Department of Oral and Maxillofacial Surgery, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India
5 Department of Oral and Maxillofacial Pathology, Chandra Dental College, Barabanki, Uttar Pradesh, India
6 Department of Conservative Dentistry, CKS Theja Dental College, Thirupati, Andhra Pradesh, India

Correspondence Address:
Chandra Sekhara Prabhahar
Department of Periodontology, Best Dental Science College, Madurai - 625 020, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2231-0762.149039

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Aim: The aim of the present study was to estimate the salivary β-glucuronidase level in healthy and diseased periodontium and to correlate the level with clinical measurement. Materials and Methods: 70 patients were included in this study with the age ranging from 30 to 65 years. Both males and females were included. They were divided into two groups: Control having healthy periodontium (n = 20) and experimental having diseased periodontium (n = 50). The parameters recorded were probing pocket depth, probing attachment level, gingival index, β-glucuronidase activity in the saliva, number of white blood cells, neutrophils, lymphocytes count, and platelet count. Results: It was observed that there was an increase in the level of salivary β-glucuronidase in the experimental subjects than in the control patients, and a significant positive linear relationship existed between salivary β-glucuronidase level and probing pocket depth in the experimental group. Conclusion: Level of salivary β-glucuronidase increases during inflammation in the periodontium.

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