| ORIGINAL ARTICLE |
|
| Year : 2022 | Volume
: 12
| Issue : 2 | Page : 252-259 |
|
|
The effect of toothpastes containing hydroxyapatite, fluoroapatite, and Zn-Mg-hydroxyapatite nanocrystals on dentin hypersensitivity: A randomized clinical trial
Maria Polyakova, Inna Sokhova, Vladlena Doroshina, Marianna Arakelyan, Nina Novozhilova, Ksenia Babina
Department of Therapeutic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Correspondence Address:
Dr. Ksenia Babina
Department of Therapeutic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 11, Mojaiskii val str, 119991 Moscow.
Russia
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jispcd.JISPCD_333_21
|
|
|
Aims: The aim of this study was to compare the effect of toothpastes containing hydroxyapatite (nHAP), Zn-Mg-hydroxyapatite (nZnMgHAP), and fluorapatite (nFAP) nanocrystals on dentin hypersensitivity (DH) associated with noncarious cervical lesions. Materials and Methods: Thirty consenting volunteers aged 35−45 years with DH were enrolled in a double-blind, parallel study, randomly assigned to the nHAP group (n = 10), the nZnMgHAP group (n = 10), or the nFAP group (n = 10), and instructed to use the toothpaste twice daily for one month. The primary outcome was Schiff scores at baseline and after 2 and 4 weeks. Results: All patients fulfilled the study requirements, and no adverse effects were registered. A reduction in DH was registered in 90%, 100%, and 50% of patients using nHAP, nZnMgHAP, and nFAP-containing toothpastes with effect sizes 2.52 (confidence interval [CI] 95%: 0.82, 4.14), 3.30 (CI 95%: 1.33, 5.20), and 1.44 (CI 95%: 0.09, 2.72), respectively. At 4 weeks, Schiff index scores decreased significantly in all groups compared to baseline. Conclusions: nZnMgHAP may be considered a promising agent for DH management. |
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
Users Online: 82
