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  Indian J Med Microbiol
 

Figure 5: The role of diabetes mellitus in generating oxidative stress due to chronic hyperglycemia and dyslipidemia. DM = diabetes mellitus, AGE = advanced glycation end products, LDL = low-density lipoprotein, [NAD(P)H] = nicotinamide adenine dinucleotide phosphate, NOS = nitric oxide synthase, SOD = superoxide dismutase, GPx = glutathione peroxidase, GR = glutathione reductase. *Amadori products give rise to Advanced Glycation End-Products (AGE’s) – ROS are generated at multiple steps during this process

Figure 5: The role of diabetes mellitus in generating oxidative stress due to chronic hyperglycemia and dyslipidemia. DM = diabetes mellitus, AGE = advanced glycation end products, LDL = low-density lipoprotein, [NAD(P)H] = nicotinamide adenine dinucleotide phosphate, NOS = nitric oxide synthase, SOD = superoxide dismutase, GPx = glutathione peroxidase, GR = glutathione reductase. *Amadori products give rise to Advanced Glycation End-Products (AGE’s) – ROS are generated at multiple steps during this process